PEPFAR Cuts Shut 1,714 HIV Sites as 73% of Partners Halt Key-Population Services

3 articles · Updated · amfAR, The Foundation for AIDS Research · Jul 21

At least 1,714 HIV service sites in 46 countries closed entirely after terminated or delayed PEPFAR payments, according to an amfAR-led study of 166 funded organizations.
A 51% drop in HIV prevention spending from fiscal 2024 to 2025 drove much of the disruption, and almost no organizations were able to replace the lost U.S. funding.
Key-population programs were hit hardest: 73% of implementing partners stopped at least one such service, 67% halted outreach, and 43% permanently ended at least one prevention activity such as condom distribution or PrEP.
Even services formally spared from the cuts were disrupted, with 64% of partners reporting interruptions to treatment, testing or mother-to-child transmission prevention, and 22% stopping that last service entirely.
The study says the cuts weakened the broader HIV delivery system that PEPFAR had helped build since 2003, threatening gains from a program credited with saving more than 26 million lives.

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11 Sources

With 1,700 HIV sites now closed, what is the true human cost behind the conflicting data on global AIDS relief?

As US aid shifts to 'country ownership,' are nations prepared to independently manage the HIV crisis and prevent a resurgence?

The Cost of U.S. HIV/AIDS Funding Cuts: Millions at Risk and a Global Health Crisis Unfolds

Overview

Recent U.S. HIV/AIDS funding cuts have plunged the global health infrastructure, especially in Africa, into a dangerous situation. This has destabilized local HIV service systems, leading to the loss of many critical health workers and prevention services. For example, the Anova Health Institute had to stop its PEPFAR-funded programs and lay off about 3,000 health workers, which severely impacted the delivery of essential services like pre-exposure prophylaxis (PrEP). As a result, decades of progress in fighting HIV/AIDS are now at risk of being reversed, putting vulnerable populations in greater danger.

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