One-Month Vegan Diet Cut Biological Age by 1.7 Years in 48-Adult Study

3 articles · Updated · studyfinds.com · Aug 11

Forty-eight healthy adults randomized to vegan or meat-rich diets for one month showed a 1.7-year drop on the PhenoAge biological aging clock in the vegan group, while the meat-rich group’s estimate edged higher.
More than 800,000 DNA methylation sites were scanned, and researchers found distinct gene-regulation changes plus significantly lower neutrophils and higher CD4+ T cells in the vegan group, matching blood-test patterns tied to lower inflammation.
Most genome-wide methylation signals — including hints that some cancer-related pathways were dialed down — lost significance after statistical correction, and a third clock tracking chronological age moved slightly in the opposite direction.
With just 24 people per group and a one-month, calorie-matched diet that allowed processed vegan foods, the authors called the findings preliminary and said larger, longer follow-up studies are needed.