Fecal Transplants Induce Peanut Tolerance in 6 of 15 Patients in Early Trial

3 articles · Updated · cleveland.com · Aug 11

Six of 15 people with severe peanut allergies developed tolerance after ingesting stool-derived capsules in an early-stage clinical trial tracked over four months.
The study, published in Science Translational Medicine, tested whether transferring gut bacteria from healthy donors could reshape the microbiome enough to reduce allergic reactions.
Researchers and outside allergists said the approach is promising because current allergy therapies often lose effect without continued treatment or exposure.
The team now plans to run the same trial in teenagers, extending early evidence that microbiome-based treatment could offer longer-lasting allergy relief.

Sources

Could swallowing gut bacteria from healthy donors be the secret to permanently erasing severe peanut allergies without daily treatments?

Why did a brief dose of antibiotics before a fecal transplant double the success rate of reversing dangerous food allergies?