Updated
Updated · University of Minnesota Twin Cities · Aug 21
HPV Vaccine Cuts Head and Neck Cancer Risk 68% in Ages 9-26 Study
Updated
Updated · University of Minnesota Twin Cities · Aug 21

HPV Vaccine Cuts Head and Neck Cancer Risk 68% in Ages 9-26 Study

3 articles · Updated · University of Minnesota Twin Cities · Aug 21

Summary

  • A 1.4 million-record study across 66 U.S. healthcare organizations found HPV-vaccinated people ages 9 to 26 were 68% less likely to be diagnosed with head or neck cancer.
  • The strongest association appeared in oropharyngeal cancers, where vaccinated people were 91% less likely to be diagnosed; no statistically significant reduction was seen for those vaccinated at ages 27 to 45.
  • Only 40 head and neck cancers occurred in the HPV-vaccinated group versus 130 in the comparison group, leading outside researchers to caution that the exact size of the benefit remains uncertain.
  • Researchers followed patients for up to 13 years, but experts said longer follow-up and larger studies are needed because these cancers are usually diagnosed later in life, around age 64.
  • The findings add to growing evidence that HPV vaccination helps prevent cancers beyond cervical disease, as HPV now causes most oropharyngeal tumors and a large share of several other cancers.

Insights

Why does the HPV vaccine's near-total protection against throat cancer suddenly vanish for adults over 26?
Could a routine childhood vaccine be the ultimate secret to preventing devastating throat cancers decades later?