Updated
Updated · Ars Technica · Sep 4
Howard Hughes, Google Complete 2nd Fruit Fly Brain Map With Hundreds of Millions of Synapses
Updated
Updated · Ars Technica · Sep 4

Howard Hughes, Google Complete 2nd Fruit Fly Brain Map With Hundreds of Millions of Synapses

3 articles · Updated · Ars Technica · Sep 4

Summary

  • Researchers on Friday unveiled a complete neuron-by-neuron map of a male fruit fly brain, creating a second full Drosophila connectome after a female brain was mapped earlier this year.
  • Hundreds of millions of synapses had to be reconstructed from ultra-high-resolution brain images, a task the Howard Hughes Janelia team and Google said required both specialized sample preparation and large-scale computer analysis.
  • The new map gives scientists a direct way to compare male and female fly brains while also serving as a research tool for studying how sensory input is transformed into memory, movement and other outputs.
  • The collaboration also refined mapping methods that researchers expect to apply to increasingly complex nervous systems, potentially extending from insects to vertebrates.

Insights

What can a 125-million-synapse map of a male fruit fly reveal about how brains turn sensation into movement?
Could the fruit fly’s newly mapped neural wiring become a blueprint for more efficient AI and robotic control?
Why do fewer than 5% of sex-specific fly neurons create outsized behavioral differences between males and females?