Imperial Study Links Top 20% Inflammation Levels to 43% Higher Heart Attack, Stroke Risk
Updated
Updated · The Times of India · Sep 20
Imperial Study Links Top 20% Inflammation Levels to 43% Higher Heart Attack, Stroke Risk
3 articles · Updated · The Times of India · Sep 20
Summary
Nearly 480,000 UK adults in the UK Biobank study showed a 43% higher risk of future heart attack or stroke among those in the highest GlycA inflammation group.
Heart scans tied that elevated inflammation to thicker heart walls, smaller chambers and poorer filling—changes seen even in people without diagnosed cardiovascular disease.
Imperial College London researchers said the pattern supports a pathway in which chronic stress sustains low-grade inflammation that quietly damages arteries and reshapes the heart over time.
Smoking, excess weight, psychological distress and fewer financial or emotional resources tracked closely with higher inflammation, pointing to modifiable risks alongside stress itself.
The findings add to evidence that prevention should start before symptoms appear, with focus on blood pressure, cholesterol, exercise, sleep, smoking cessation and mental health.