UGA Researchers Develop 3D Real-Time Seizure Imaging System for Brain Activity

1 articles · Updated · Radiology Business · Aug 13

University of Georgia researchers built a high-resolution imaging system that captures seizures in 3D and in real time, aiming to show how abnormal activity starts, spreads and stops in the brain.
The setup combines light-sheet microscopy with adaptive optics, using thin planes of light for fast imaging and correcting tissue-driven distortions that can blur views inside living brains.
Tests in zebrafish larvae tracked one seizure from onset to end, showing activity begin at the back of the brain, move toward the optic tecta and then fade over several seconds.
The team said moving from 2D to 3D imaging could reveal seizure pathways that flat images miss and help researchers better pinpoint where episodes originate and how they propagate.