Study Links Long-Term Tadalafil Use to 22% Higher Glaucoma Risk in Men
Updated
Updated · SciTechDaily · Aug 14
Study Links Long-Term Tadalafil Use to 22% Higher Glaucoma Risk in Men
3 articles · Updated · SciTechDaily · Aug 14
Summary
73,854 men aged 40 or older were tracked for up to five years, and those prescribed tadalafil or another PDE5 inhibitor for urinary symptoms showed a 22% higher likelihood of developing glaucoma.
The analysis also found 32% higher odds of ocular hypertension, 33% higher risk of primary open-angle glaucoma, and a 33% greater chance of starting glaucoma treatment.
Researchers said the pattern persisted within 1, 3 and 6 months of starting tadalafil and across older, White and medically complex patient groups after matching for major health factors.
Because the study was observational, it cannot prove tadalafil caused the eye risks, but the authors said long-term users—especially men with existing glaucoma risk factors—may need baseline eye exams and regular follow-up.